Hypothesis:

There is evidence that gluten intolerance causes neurological problems.   Since gluten antibodies bind to intestinal cells to produce the damage and symptoms of celiac disease, they should bind to proteins in the brain to produce behavioral effects.

Materials: 

Some brain tissue and a mixture of radioactively labeled gluten antibodies.

A lab full of high tech machines to analyze the results.

Method: 

Mix the antibodies with the tissue, wait a while, wash off the excess and then look for radioactive traces on the brain tissue.

Filter/separate the radiolabeled complexes and analyze.

Results:

Only IgG antibodies adhered to the brain tissue, Not IgA.

Not all the IgG antibodies adhered to the brain tissue.

The binding site is a protein called synapsin I.

They then looked for evidence in patients and found antigliadin-synapsin complexes in their blood.

Conclusion

This experiment shows that a subset of the IgG isotype gluten antibodies indeed bind to proteins in the brain.  This portion of the IgG antibodies bind to the Synapsin I protein, and these complexes appear in human patients.   Evidence shows that Synapsin I is involved with neurotransmitter transport so these results are consistent with and provide a possible mechanism for neurological impairment caused by gluten intolerance.